Nobel Prize in medicine goes to two American biologists for work on the discovery of microRNA The 2024 Nobel Prize in physiology or medicine has been awarded to US scientists Victor Ambros and Gary Ruvkun for their work on the discovery of microRNA, a molecule that governs how cells in the body function.

Diabetes mellitus has been completely cured for the first time in the world For the first time, scientists transplanted stem cells into a woman with type 1 diabetes, after which she began to produce her own insulin. This is the world's first case of treatment using cells taken from the patient's body.

New Hypertension Approach Hits Multiple Targets at Low Dose Single-pill combinations that include three or four antihypertensive medications are the way forward for the management of patients with elevated blood pressure, according to experts evaluating the new approach.

Emerging role of incretin-based therapy as first-line antihypertensives in obesity Obesity is a major global health issue and a leading cause of premature death. The prevalence of obesity has been rising faster than most other known modifiable risk factors. In a Global Burden of Disease analysis, the prevalence of obesity was found to have doubled in more than 70 countries from 1980 to 2013.

A new app uses smartphone technology to 'uncuff' blood pressure monitoring Researchers at the University of Pittsburgh are pioneering a new approach to blood pressure monitoring—using the devices we carry with us every day.

New Blood Pressure Guidelines Lower Treatment Target Simplified and more aggressive targets are among the significant changes to the updated hypertension guidelines released by the European Society of Cardiology.

New Atrial Fibrillation Guidelines Confront Underlying Illness Updated guidelines for the management of atrial fibrillation released by the European Society of Cardiology are revamping the approach to care for this complex, multifactorial disease.

In situ assembly of an injectable cardiac stimulator Without intervention, cardiac arrhythmias pose a risk of fatality. However, timely intervention can be challenging in environments where transporting a large, heavy defibrillator is impractical, or emergency surgery to implant cardiac stimulation devices is not feasible. Here, we introduce an injectable cardiac stimulator, a syringe loaded with a nanoparticle solution comprising a conductive polymer and a monomer that, upon injection, forms a conductive structure around the heart for cardiac stimulation.

Polycystic Ovary Syndrome: A Hidden Risk for Metabolic and Cardiovascular Diseases? Women with polycystic ovary syndrome (PCOS) face an increased risk for type 2 diabetes (T2D), metabolic dysfunction–associated steatotic liver disease (MASLD), and cardiovascular disease (CVD), although these risks vary depending on PCOS phenotype.

Can Electronic Decision Support Improve Acute Heart Failure Care in EDs? An electronic decision support tool may increase the prescription of guideline–directed medical therapy for patients with acute heart failure (AHF) in emergency departments (EDs), with no serious adverse events (SAEs) within 30 days among very low-risk patients who are discharged.