Nobel Prize in Physiology or Medicine 2025
The Nobel Prize in Physiology or Medicine 2025 was awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance.
World Heart day 2025
World Heart Day is celebrated annually on September 29. Since its inception, the Cardioprogress Foundation has actively collaborated with the World Heart Federation and, to celebrate this occasion, organizes events in various cities across the Russian Federation.
ACC and AHA guidelines for the treatment of hypertension have been updated
The target blood pressure level for adults remains below 130/80 mm Hg, but drug therapy should be initiated sooner, according to new guidelines published by the American Heart Association (AHA) and American College of Cardiology (ACC). Eleven other medical organizations endorsed the new guidelines, which replace those issued in 2017.
A new risk stratification tool
A new risk stratification tool known as CA4TCH — which relies solely on clinical history — could help predict which patients with a suspected hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) will have a hypersensitivity confirmed during a drug provocation test.
First Major Guidelines Issued for Left Atrial Appendage Occlusion Devices
Created to address the “uncertainty and practice variation” that surrounds transcatheter left atrial appendage occlusion (LAAO), the Society for Cardiovascular Angiography and Interventions and the Heart Rhythm Society have published jointly the first set of guidelines for the use of the procedure.
Your Heart May Be Older Than You Think
Some people are said to have old souls. Some may have old hearts, too. Many Americans, particularly men with less education, lower income, and those from certain minority groups, have a “heart age” that is much older than what the calendar may indicate.
Lp(a) Levels: When and Why It’s Clinically Relevant
The presence of high lipoprotein (a), or Lp(a), levels increases the risk for cardiovascular disease. Incorporating Lp(a) screening into clinical practice may significantly impact patient outcomes.
APOE4 May Raise Brain Bleed Risk in Apixaban Users With AF
Carriers of the apolipoprotein E epsilon 4 (APOE ε4) allele had a threefold higher risk for intracranial hemorrhage (ICH) when taking apixaban for atrial fibrillation (AF) compared with noncarriers, a new study suggested.
Novel Algorithm Transforms Echocardiographic Assessment of Heart Filling Pressures
A new algorithm for estimating left ventricular filling pressure (LVFP) by echocardiography reduced indeterminate results to just two cases compared with 38 using previous guidelines, achieving 86% accuracy in 949 patients, a new study found. The algorithm showed particular improvement for patients with normal left ventricular ejection fraction (LVEF), while maintaining similar accuracy for cases of reduced LVEF.
Novel GLP-1 Agonist Promotes Safe and Effective Weight Loss
Ecnoglutide, a novel glucagon-like peptide-1 (GLP-1) receptor agonist, was significantly more effective than placebo for inducing weight loss in adults with overweight or obesity, based on data from more than 600 individuals.