New guidelines may help prevent sudden death in myocarditis
The European Society of Cardiology (ESC) recently released its 2025 guidelines for the management of myocarditis, which also includes extensive discussion of pericarditis and the wide range of overlap between these types of cardiac inflammation. The guidelines were presented at the ESC Congress 2025 in Madrid and simultaneously published in the European Heart Journal.
Nobel Prize in Physiology or Medicine 2025
The Nobel Prize in Physiology or Medicine 2025 was awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance.
New Hypertension Approach Hits Multiple Targets at Low Dose
Single-pill combinations that include three or four antihypertensive medications are the way forward for the management of patients with elevated blood pressure, according to experts evaluating the new approach.
Emerging role of incretin-based therapy as first-line antihypertensives in obesity
Obesity is a major global health issue and a leading cause of premature death. The prevalence of obesity has been rising faster than most other known modifiable risk factors. In a Global Burden of Disease analysis, the prevalence of obesity was found to have doubled in more than 70 countries from 1980 to 2013.
A new app uses smartphone technology to 'uncuff' blood pressure monitoring
Researchers at the University of Pittsburgh are pioneering a new approach to blood pressure monitoring—using the devices we carry with us every day.
New Blood Pressure Guidelines Lower Treatment Target
Simplified and more aggressive targets are among the significant changes to the updated hypertension guidelines released by the European Society of Cardiology.
New Atrial Fibrillation Guidelines Confront Underlying Illness
Updated guidelines for the management of atrial fibrillation released by the European Society of Cardiology are revamping the approach to care for this complex, multifactorial disease.
In situ assembly of an injectable cardiac stimulator
Without intervention, cardiac arrhythmias pose a risk of fatality. However, timely intervention can be challenging in environments where transporting a large, heavy defibrillator is impractical, or emergency surgery to implant cardiac stimulation devices is not feasible. Here, we introduce an injectable cardiac stimulator, a syringe loaded with a nanoparticle solution comprising a conductive polymer and a monomer that, upon injection, forms a conductive structure around the heart for cardiac stimulation.
Polycystic Ovary Syndrome: A Hidden Risk for Metabolic and Cardiovascular Diseases?
Women with polycystic ovary syndrome (PCOS) face an increased risk for type 2 diabetes (T2D), metabolic dysfunction–associated steatotic liver disease (MASLD), and cardiovascular disease (CVD), although these risks vary depending on PCOS phenotype.
Can Electronic Decision Support Improve Acute Heart Failure Care in EDs?
An electronic decision support tool may increase the prescription of guideline–directed medical therapy for patients with acute heart failure (AHF) in emergency departments (EDs), with no serious adverse events (SAEs) within 30 days among very low-risk patients who are discharged.