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Scientific news

  • Cardiovascular Benefits of Semaglutide in SELECT Trial Not Fully Explained by Weight Loss and Other Improvements In adults with obesity and established cardiovascular disease (CVD), semaglutide was associated with improvements in several risk factors. However, those changes only accounted for part of the reduced risk for major adverse cardiovascular events (MACE) noted in the SELECT trial.

  • Peripheral Artery Disease Linked to Higher Risk for Mortality Post-Kidney Transplant Among kidney transplant recipients aged 65 years or older, peripheral artery disease was independently associated with an increased risk for mortality in the first year post-transplant. Chronological age was not independently associated with mortality overall, although recipients older than 75 years showed a trend towards a higher risk for mortality.

  • Role of routine surveillance stress testing in patients with or without imaging-guided or physiology-guided PCI The analysis of the randomized study “Pragmatic Comparison of Symptomatic and Routine Stress Testing in High‑Risk Patients Who Underwent PCI” showed that the routine strategy of follow‑up functional testing 1 year after percutaneous coronary intervention does not reduce the risk of death, myocardial infarction, or hospitalization due to unstable angina within 2 years. At the same time, it more often leads to invasive coronary angiography and repeat revascularization without clinical benefit.

  • Intense Septal Enhancement on Cardiac MRI Flags Cardiac Amyloidosis A retrospective study showed that intensive gadolinium contrast enhancement of the anterior interatrial septum during cardiac magnetic resonance imaging, with a high degree of specificity (98%), makes it possible to diagnose cardiac amyloidosis when compared with hypertrophic cardiomyopathy and dilated cardiomyopathy.

  • Weight Loss During Heart Failure Hospitalization Linked to Lower 30-Day Rehospitalization Risk Patients hospitalized for heart failure who were treated with intravenous loop diuretics and achieved a weight loss of at least 2 kg between admission and discharge had a reduced risk for HF rehospitalization within 30 days.

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