CARDIOPROGRESS
Foundation for the advancement of cardiology

Prasugrel Bests Ticagrelor in Acute Coronary Syndrome Care Prasugrel is associated with lower rates of mortality, myocardial infarction (MI), and stroke than ticagrelor under conditions of routine care of patients discharged after invasive treatment for acute coronary syndrome, with the effects being particularly pronounced in those with ST-segment elevation MI (STEMI).

Smarter Pregnancy App Links Improved Lifestyle Habits to Lower Maternal Blood Pressure in Early Pregnancy Digital lifestyle coaching through the Smarter Pregnancy program reduces maternal blood pressure (BP) by approximately 2 mmHg during the first trimester of pregnancy. The program enhances lifestyle behaviors through personalized coaching on vegetable and fruit intake, smoking cessation, and alcohol abstinence.

Mobile Stroke Units Linked to Improved OutcomesAmong Patients WithAcute Ischemic Stroke Patients with acute ischemic stroke treated in mobile stroke units have better outcomes, with lower global disability scores, faster thrombolysis times, and comparable safety outcomes, than those receiving standard emergency medical services (EMS) care.

Decision Support Tool Fails to Boost Anticoagulation Initiation in US Emergency Departments A multipronged intervention in US emergency departments (EDs) has been found to not significantly increase anticoagulation initiation within 30 days of discharge for patients with primary atrial fibrillation or flutter (AFF).

Motor vehicle crash risk after cardioverter-defibrillator implantation Limited empirical evidence informs driving restrictions after implantable cardioverter-defibrillator (ICD) implantation. We sought to evaluate real-world motor vehicle crash risks after ICD implantation.

Exercise training improves cardiovascular fitness in dilated cardiomyopathy caused by truncating titin variants Participation in regular exercise activities is recommended for patients with chronic heart failure. However, less is known about the effect of exercise in patients with genetic dilated cardiomyopathy (DCM). We sought to examine the effect of vigorousintensity training on physical capacity in patients with DCM caused by truncating titin variants (TTNtv).

Managing cardiogenic shock and left ventricular outflow tract obstruction in Takotsubo syndrome: current insights and challenges Over the past decade, Takotsubo syndrome (TTS) has gained increasing recognition as a serious acute cardiovascular condition and now represents an important differential diagnosis in patients with suspected acute coronary syndrome. Current evidence suggests that TTS is likely related to a catecholamine storm leading to coronary microvascular dysfunction in the absence of epicardial coronary artery culprit lesion.

The impact of COVID-19 vaccination on patients with congenital heart disease in England: a case-control study Studies predating widespread COVID-19 vaccination identified patients with congenital heart disease (CHD) as a group at increased risk of severe outcomes from COVID-19. Here we evaluate the impact of vaccination on COVID-19 outcomes among patients with CHD.

Brain Recovery at Discharge Predicts Survival After Cardiac Arrest Cardiac arrest survivors with complete neurologic recovery at hospital discharge show significantly improved long-term survival rates, found a study.

Percutaneous coronary intervention plus medical therapy versus medical therapy alone in chronic coronary syndrome: a propensity score-matched analysis from the Swedish Coronary Angiography an Percutaneous coronary intervention (PCI) is frequently used for patients with chronic coronary syndrome (CCS). However, the role of PCI beyond symptom relief in CCS remains controversial. The objective of this study was to determine whether PCI is associated with better outcomes, compared with medical therapy (MT) alone.

ADA Advises Against Using Compounded GLP-1 RA Medications In a new statement, the American Diabetes Association (ADA) has advised against the use of compounded glucagon-like peptide 1 receptor agonist (GLP-1 RA) and dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 RA medication classes.

New Trial Result Pushes Past Antiarrhythmic Therapy After MI For ventricular tachycardia after myocardial infarction, outcomes are better with upfront catheter ablation than drug therapy, which is typically used first, the multinational VANISH2 trial shows.

New Pill Successfully Lowers Lp(a) Levels Muvalaplin, a novel oral medication, safely and effectively lowers high levels of lipoprotein(a), or Lp(a), results from the phase 2 KRAKEN trial show.

The results of the 35th International Congress of Cardiology "Great Wall" and the Asian Congress of Cardiology 2024 The anniversary 35th International Congress of Cardiology "Great Wall" and the Asian Congress of Cardiology were held in Beijing at the National Exhibition Center on November 7-10, 2024. As part of the four-day congress, 415 scientific sessions were organized and 2177 reports were made on various areas of cardiology. The congress was attended by 23,980 national and international experts, professors and specialists from almost 40 countries from all the continents of the world.

New State Law Will Restrict AI in Prior Authorization, Coverage Decisions California is taking aim at algorithms used by insurers to make prior authorization and other coverage decisions with a new law that will put limitations on how artificial intelligence (AI)–generated formulas are employed.

Development and validation of a machine learning model to predict myocardial blood flow and clinical outcomes from patients’ electrocardiograms Scientists have developed a machine learning (ML) model using electrocardiography (ECG) to predict myocardial blood flow reserve (MFR) and assess its predictive value in relation to major adverse cardiovascular events (MACEs). Using 3639 ECG positron emission tomography (PET) and 17,649 pairs of ECG single-photon emission computed tomography data (SPECT), the model is trained using the intelligent swarm intelligence approach and support vector regression (SVR).

New Scanner Creates Highly Detailed, 3D Images of Blood Vessels in Just Seconds A new scanner can provide three-dimensional (3D) photoacoustic images of millimeter-scale veins and arteries in seconds.

Nobel Prize in medicine goes to two American biologists for work on the discovery of microRNA The 2024 Nobel Prize in physiology or medicine has been awarded to US scientists Victor Ambros and Gary Ruvkun for their work on the discovery of microRNA, a molecule that governs how cells in the body function.

Diabetes mellitus has been completely cured for the first time in the world For the first time, scientists transplanted stem cells into a woman with type 1 diabetes, after which she began to produce her own insulin. This is the world's first case of treatment using cells taken from the patient's body.

New Hypertension Approach Hits Multiple Targets at Low Dose Single-pill combinations that include three or four antihypertensive medications are the way forward for the management of patients with elevated blood pressure, according to experts evaluating the new approach.