CARDIOPROGRESS
Foundation for the advancement of cardiology

Impact of multiple obesity metrics on hypertensive disorders of pregnancy: a meta-analysis and Mendelian randomisation study This study demonstrates that various obesity measures are causally linked to increased HDP risk and highlights the mediating role of triglycerides. These findings could inform clinical practices and public health strategies aimed at reducing HDP through targeted obesity and triglyceride management.

Optimal treatment of symptomatic patients with low-gradient severe Aortic valve Stenosis and preserved left ventricular ejection fraction (ROTAS trial) The best management of symptomatic patients with low-gradient (LG) severe aortic stenosis (AS) and preserved left ventricular ejection fraction (LVEF) has not been established.

Cardiovascular safety of vitamin B3 administration Scientists recently reported associations between serum levels of the terminal niacin metabolites N1-methyl-2-pyridone-5-carboxamide (2PY) and N1-methyl-4-pyridone-3-carboxamide (4PY) with an increased 3-year incident risk of major adverse cardiovascular events.

Semaglutide Reduces MACE, Death in Participants With CVD, Overweight/Obesity, and Impaired Kidney Function Semaglutide (Wegovy) prevents major cardiac events including death in adults with overweight/obesity and cardiovascular disease (CVD), both with and without impaired kidney function, a subgroup analysis of the Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity (SELECT) trial shows.

Persistence of residual shunt at 6 and 12 months after transoesophageal echocardiography-guided percutaneous closure of a patent foramen ovale for cryptogenic stroke Young patients suffering from cryptogenic stroke alongside a patent foramen ovale (PFO) are often considered for percutaneous device closure to reduce the risk of stroke recurrence. Residual right-to-left shunt after device closure may persist in approximately a quarter of the patients at 6 months, and some may close at a later time point.

Can AI Improve Cardiomyopathy Detection in Pregnant Women? Artificial intelligence (AI)–guided screening using digital stethoscopes doubled the detection of left ventricular systolic dysfunction (LVSD) in pregnant and postpartum women in Nigeria.

Study shows cardiovascular health benefits can begin shortly after quitting smoking Quitting cigarettes can significantly lower a person's risk of atrial fibrillation (AFib) compared to those who continue to smoke, according to a study published in JACC: Clinical Electrophysiology. The findings show that the benefits of quitting start right away, suggesting that it is possible to reverse the risk of negative health outcomes.

Balloon Angioplasty Plus Medical Management for sICAS. Study Adding balloon angioplasty to aggressive medical management significantly lowers the risk for stroke or death in patients with symptomatic intracranial atherosclerotic stenosis (sICAS), results of a new randomized clinical trial showed.

Pilot: OCT Parameter Tracks Atherosclerosis Progression The histopathological status of an atherosclerotic plaque can not only be quantified but also tracked over time by using a parameter calculated from optical coherence tomography (OCT) images, researchers from the Chinese PLA General Hospital in Beijing, China, have found.

Prehospital Cardiac Pacing Linked to High Mortality Rate in Patients With Bradycardia A recent study has found prehospital transcutaneous cardiac pacing (TCP) in patients with bradycardia to be associated with a high mortality rate of 63.4%, and TCP failure associated with increased body weight, non-bradycardic initial heart rate, and pre-TCP hypoxia.

Ross Procedure Making a Comeback in Aortic Valve Disease The Ross procedure, which can be used to treat young people with severe aortic valve disease, has seen wide swings in popularity over the years, but now, with consistent data on long-term survival and valve durability, numbers are steadily climbing again.

AHA Advisory Endorses Endovascular Thrombectomy for Large Core Ischemic Stroke Results of six recent trials of endovascular thrombectomy (EVT) for patients with large-core ischemic stroke (LCIS) provide strong evidence for the benefit of this intervention compared with medical management (MM), a new Science Advisory from the American Heart Association (AHA) has concluded.

Emerging role of incretin-based therapy as first-line antihypertensives in obesity Obesity is a major global health issue and a leading cause of premature death. The prevalence of obesity has been rising faster than most other known modifiable risk factors. In a Global Burden of Disease analysis, the prevalence of obesity was found to have doubled in more than 70 countries from 1980 to 2013.

A new app uses smartphone technology to 'uncuff' blood pressure monitoring Researchers at the University of Pittsburgh are pioneering a new approach to blood pressure monitoring—using the devices we carry with us every day.

New Blood Pressure Guidelines Lower Treatment Target Simplified and more aggressive targets are among the significant changes to the updated hypertension guidelines released by the European Society of Cardiology.

New Atrial Fibrillation Guidelines Confront Underlying Illness Updated guidelines for the management of atrial fibrillation released by the European Society of Cardiology are revamping the approach to care for this complex, multifactorial disease.

In situ assembly of an injectable cardiac stimulator Without intervention, cardiac arrhythmias pose a risk of fatality. However, timely intervention can be challenging in environments where transporting a large, heavy defibrillator is impractical, or emergency surgery to implant cardiac stimulation devices is not feasible. Here, we introduce an injectable cardiac stimulator, a syringe loaded with a nanoparticle solution comprising a conductive polymer and a monomer that, upon injection, forms a conductive structure around the heart for cardiac stimulation.

Polycystic Ovary Syndrome: A Hidden Risk for Metabolic and Cardiovascular Diseases? Women with polycystic ovary syndrome (PCOS) face an increased risk for type 2 diabetes (T2D), metabolic dysfunction–associated steatotic liver disease (MASLD), and cardiovascular disease (CVD), although these risks vary depending on PCOS phenotype.

Can Electronic Decision Support Improve Acute Heart Failure Care in EDs? An electronic decision support tool may increase the prescription of guideline–directed medical therapy for patients with acute heart failure (AHF) in emergency departments (EDs), with no serious adverse events (SAEs) within 30 days among very low-risk patients who are discharged.

Evaluation of the World Health Organization-HEARTS hypertension control package in Bangladesh: a quasi-experimental trial The World Health Organization (WHO) promotes the HEARTS technical package for improving hypertension control worldwide, but its effectiveness has not been rigorously evaluated.