As Herceptin Goes Off Patent, ’Biosimilars’ Emerge
SAN ANTONIO — As the epoch-making breast cancer targeted therapy trastuzumab (Herceptin, Genentech) is coming to the end of its patent protection, a new kind of knock-off product is being developed to compete in the drug’s large market.
Head Blows Linked to Brain Changes, Even Without Concussion
Even in the absence of a concussion, repeated blows to the head during a season of US football or ice hockey appear to be associated with changes in brain white matter and may also be linked to reduced cognition, a new study shows.
Glaxo’s New Doc-Pay Policy Mostly Pleases Critics
The recent decision by GlaxoSmithKline to stop paying physicians to promote its drugs and reform other marketing practices represents progress, Big Pharma critics told Medscape Medical News, but some said the company can’t stop there.
New SGR Repeal Bill Includes Slight Pay Hikes
Robert Lowes
Facing a March 31 deadline to avert catastrophe in medical practices, a bipartisan group of House and Senate members today introduced a bill that would repeal Medicare’s sustainable growth rate (SGR) formula for setting physician reimbursement.
First AHA/ASA Guidelines to Reduce Stroke Risk in Women
Sue Hughes
The American Heart Association/American Stroke Association (AHA/ASA) has issued the first guidelines for reducing stroke risk specifically in women.
Fruit, Tea, and Wine Could Guard Against Type 2 Diabetes
Lisa Nainggolan
A new study in healthy women suggests that consuming high levels of flavonoids, including compounds found in berries, tea, grapes, and wine, could potentially lower the risk of type 2 diabetes.
Gout Incidence Increasing, but Most Patients Go Untreated
Janis C. Kelly
Previous hopes that gout incidence and prevalence had plateaued in the United Kingdom were dashed by a new report published online January 15 in the Annals of the Rheumatic Diseases.
Caffeine: No Downside, Hint of Benefit in Atrial Fibrillation
A meta-analysis from Chinese researchers has concluded that there is an inverse relationship between regular caffeine consumption and atrial fibrillation risk.
“International Heart and Vascular Disease Journal”
The International Heart and Vascular Disease Journal is a peer-reviewed medical journal for specialists in cardiology. The journal is published four times a year in two languages (English and Russian), in both print and digital formats. The limited-distribution print version is provided for free. All issues are available for free online at, www.cardioprogress.ru
Take Family History in Every New Cancer Patient, Says ASCO
Zosia Chustecka
Oncologists seeing a new patient with cancer should take a family history, specifically asking about cancer in first- and second-degree relatives, says the American Society of Clinical Oncology (ASCO) in a new expert statement.
Development and validation of a machine learning model to predict myocardial blood flow and clinical outcomes from patients’ electrocardiograms
Scientists have developed a machine learning (ML) model using electrocardiography (ECG) to predict myocardial blood flow reserve (MFR) and assess its predictive value in relation to major adverse cardiovascular events (MACEs). Using 3639 ECG positron emission tomography (PET) and 17,649 pairs of ECG single-photon emission computed tomography data (SPECT), the model is trained using the intelligent swarm intelligence approach and support vector regression (SVR).
New Scanner Creates Highly Detailed, 3D Images of Blood Vessels in Just Seconds
A new scanner can provide three-dimensional (3D) photoacoustic images of millimeter-scale veins and arteries in seconds.
Mediterranean Diet With Olive Oil Boosted HDL Function?
More research suggests that a Mediterranean-style diet supplemented with either virgin olive oil or mixed nuts enhances the function of HDL cholesterol[1].
In a subset of 296 patients at high risk of heart disease in thePREDIMED study, cholesterol efflux capacity (CEC), the first step in reverse cholesterol transport, was significantly increased at 1 year compared with baseline in those advised to eat a Mediterranean diet rich in virgin olive oil (VOO) (P=0.018) or mixed nuts (P=0.013) rather than a reduced-fat diet.
International Heart and Vascular Disease Journal-Issues
International Heart and Vascular Disease Journal
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