Mobile Stroke Units Linked to Improved OutcomesAmong Patients WithAcute Ischemic Stroke
Patients with acute ischemic stroke treated in mobile stroke units have better outcomes, with lower global disability scores, faster thrombolysis times, and comparable safety outcomes, than those receiving standard emergency medical services (EMS) care.
Decision Support Tool Fails to Boost Anticoagulation Initiation in US Emergency Departments
A multipronged intervention in US emergency departments (EDs) has been found to not significantly increase anticoagulation initiation within 30 days of discharge for patients with primary atrial fibrillation or flutter (AFF).
Motor vehicle crash risk after cardioverter-defibrillator implantation
Limited empirical evidence informs driving restrictions after implantable cardioverter-defibrillator (ICD) implantation. We sought to evaluate real-world motor vehicle crash risks after ICD implantation.
Exercise training improves cardiovascular fitness in dilated cardiomyopathy caused by truncating titin variants
Participation in regular exercise activities is recommended for patients with chronic heart failure. However, less is known about the effect of exercise in patients with genetic dilated cardiomyopathy (DCM). We sought to examine the effect of vigorousintensity training on physical capacity in patients with DCM caused by truncating titin variants (TTNtv).
Managing cardiogenic shock and left ventricular outflow tract obstruction in Takotsubo syndrome: current insights and challenges
Over the past decade, Takotsubo syndrome (TTS) has gained increasing recognition as a serious acute cardiovascular condition and now represents an important differential diagnosis in patients with suspected acute coronary syndrome. Current evidence suggests that TTS is likely related to a catecholamine storm leading to coronary microvascular dysfunction in the absence of epicardial coronary artery culprit lesion.
The impact of COVID-19 vaccination on patients with congenital heart disease in England: a case-control study
Studies predating widespread COVID-19 vaccination identified patients with congenital heart disease (CHD) as a group at increased risk of severe outcomes from COVID-19. Here we evaluate the impact of vaccination on COVID-19 outcomes among patients with CHD.
Brain Recovery at Discharge Predicts Survival After Cardiac Arrest
Cardiac arrest survivors with complete neurologic recovery at hospital discharge show significantly improved long-term survival rates, found a study.
Percutaneous coronary intervention plus medical therapy versus medical therapy alone in chronic coronary syndrome: a propensity score-matched analysis from the Swedish Coronary Angiography an
Percutaneous coronary intervention (PCI) is frequently used for patients with chronic coronary syndrome (CCS). However, the role of PCI beyond symptom relief in CCS remains controversial. The objective of this study was to determine whether PCI is associated with better outcomes, compared with medical therapy (MT) alone.
Maternal Serum Folate Levels During Pregnancy Linked to Congenital Heart Disease Risk
Maternal serum folate levels during early to midpregnancy show a U-shaped association with congenital heart disease (CHD) risk in offspring. Both low and high folate levels are linked to an increased risk, with vitamin B12 deficiency and elevated homocysteine levels further exacerbating this risk.
AI Excludes Heart Attack Better Than Specialist Criteria
A machine-learning–based artificial intelligence (AI) program developed by German researchers rapidly and easily rules out a heart attack in patients presenting with chest pain in the emergency department. In a retrospective study, the program named ARTEMIS performed significantly better than traditional diagnostic criteria.
Upcoming Joint Guidelines to Address Obesity Management
Upcoming evidence-based clinical guidelines from three obesity organizations will address US-based pharmacologic management of overweight/obesity and its complications in adults.
Resistant hypertension: a new look
Modern management of patients with arterial hypertension requires a consistent approach to treatment and prevention, with particular attention paid to the problem of low adherence to treatment. Lifestyle optimization and elimination of secondary hypertension causes are identified as key strategies.
New Blood Pressure Guidelines Lower Treatment Target
Simplified and more aggressive targets are among the significant changes to the updated hypertension guidelines released by the European Society of Cardiology.
New Atrial Fibrillation Guidelines Confront Underlying Illness
Updated guidelines for the management of atrial fibrillation released by the European Society of Cardiology are revamping the approach to care for this complex, multifactorial disease.
In situ assembly of an injectable cardiac stimulator
Without intervention, cardiac arrhythmias pose a risk of fatality. However, timely intervention can be challenging in environments where transporting a large, heavy defibrillator is impractical, or emergency surgery to implant cardiac stimulation devices is not feasible. Here, we introduce an injectable cardiac stimulator, a syringe loaded with a nanoparticle solution comprising a conductive polymer and a monomer that, upon injection, forms a conductive structure around the heart for cardiac stimulation.
Polycystic Ovary Syndrome: A Hidden Risk for Metabolic and Cardiovascular Diseases?
Women with polycystic ovary syndrome (PCOS) face an increased risk for type 2 diabetes (T2D), metabolic dysfunction–associated steatotic liver disease (MASLD), and cardiovascular disease (CVD), although these risks vary depending on PCOS phenotype.
Can Electronic Decision Support Improve Acute Heart Failure Care in EDs?
An electronic decision support tool may increase the prescription of guideline–directed medical therapy for patients with acute heart failure (AHF) in emergency departments (EDs), with no serious adverse events (SAEs) within 30 days among very low-risk patients who are discharged.
Evaluation of the World Health Organization-HEARTS hypertension control package in Bangladesh: a quasi-experimental trial
The World Health Organization (WHO) promotes the HEARTS technical package for improving hypertension control worldwide, but its effectiveness has not been rigorously evaluated.
Common Eye Disorder May Be Linked to Maternal Hypertension
Children whose mothers have a hypertensive disorder in pregnancy (HDP) may have an increased risk for strabismus, including exophoria and intermittent exotropia, new research shows. Preeclampsia and poorly controlled blood pressure may confer the greatest risk.
PET Imaging Finds Vulnerable Plaques That Cause MI
A new technique that can locate vulnerable coronary plaques at risk of rupturing and causing a myocardial infarction (MI) could help identify patients at high cardiovascular risk who might need more intensive treatment.