Brain Recovery at Discharge Predicts Survival After Cardiac Arrest

Researchers analyzed data from four Swedish mandatory national registers between January 2010 and December 2019.
This study included 9390 cardiac arrest survivors (median age, 69 years; 69.7% men) who survived at least 30 days after cardiac arrest.
The primary outcome was the survival rate based on neurologic recovery at discharge, assessed using the Cerebral Performance Category (CPC) scale; on the basis of CPC scores, patients were grouped into those with complete recovery (CPC 1), those with moderate disabilities (CPC 2), and those with severe disabilities (CPC 3-4).

At discharge, 78.5%, 14.5%, and 7.0% patients had a CPC score of 1, 2, and 3 or 4, respectively.
At 5 years, survival rates were highest among patients with complete neurologic recovery (73.8%), followed by the CPC 2, (64.7%) and CPC 3-4 (54.2%) groups.
The risk for death was 1.57 times and 2.46 times higher for those in the CPC 2 and CPC 3-4 groups, respectively, than for those in the CPC 1 group.
The associations between neurologic recovery and long-term survival were similar across out-of-hospital and in-hospital cardiac arrest survivors.

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