More Fat Around Heart Linked to Greater Injury After MI

METHODOLOGY:

In this prospective multicenter study, researchers evaluated whether the volume of epicardial adipose tissue was linked to the severity of myocardial injury after an acute MI.
They enrolled 1168 patients who underwent cardiovascular magnetic resonance imaging within 10 days after a percutaneous coronary intervention following an acute MI.
Patients were divided into quartiles based on the volumes of epicardial adipose tissue.

A higher volume of epicardial adipose tissue was independently associated with a greater size of infarct (P = .032) and larger areas at risk (P = .018) but a lower microvascular obstruction (P = .012).
Researchers found no significant differences in left ventricular ejection fraction between patients with larger and smaller volumes of epicardial adipose tissue.
Patients in the upper quartile of volume of epicardial adipose tissue were older than those in the lower quartile (66 vs 63 years; P = .002) and had higher BMI (28.9 vs 27.4; P = .001).

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